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Dr. Yasser El-Sherbiny

MTIF Fellow, Human Immunology and Cell Biology

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Srikanth S, Woo JS, Wu B, El-Sherbiny YM, Leung J, Chupradit K, Rice L, Seo GJ, Calmettes G, Ramakrishna C, Cantin E, An DS, Sun R, Wu TT, Jung JU, Savic S, Gwack Y. The Ca(2+) sensor STIM1 regulates the type I interferon response by retaining the signaling adaptor STING at the endoplasmic reticulum. Nat Immunol. 2019 Feb;20(2):152-162.

El-Sherbiny YM, El-Jawhari JJ, Moseley TA, McGonagle D, Jones E. T cell immunomodulation by clinically used allogeneic human cancellous bone fragments: a potential novel immunotherapy tool. Sci Rep. 2018 Sep 10;8(1):13535.

Md Yusof MY, Psarras A, El-Sherbiny YM, Hensor EMA, Dutton K, Ul-Hassan S, Zayat AS, Shalbaf M, Alase A, Wittmann M, Emery P, Vital EM. Prediction of autoimmune connective tissue disease in an at-risk cohort: prognostic value of a novel two-score system for interferon status. Ann Rheum Dis. 2018 Oct;77(10):1432-1439.

El-Sherbiny YM, Psarras A, Md Yusof MY, Hensor EMA, Tooze R, Doody G, Mohamed AAA, McGonagle D, Wittmann M, Emery P, Vital EM. A novel two-score system for interferon status segregates autoimmune diseases and correlates with clinical features. Sci Rep. 2018 Apr 11;8(1):5793.

Liakouli V, Elies J, El-Sherbiny YM, Scarcia M, Grant G, Abignano G, Derrett-Smith EC, Esteves F, Cipriani P, Emery P, Denton CP, Giacomelli R, Mavria G, Del Galdo F. Scleroderma fibroblasts suppress angiogenesis via TGF-ß/caveolin-1 dependent secretion of pigment epithelium-derived factor. Ann Rheum Dis. 2018 Mar;77(3):431-440.


Areas of Expertise

  • Immunology
  • Cell Biology
  • Stem Cell Research
  • Flow Cytometry
  • Polymerase chain reaction (PCR) Analysis
  • Genetically Modified Cells
  • Exosomes and MicrovesiclesApplication of Biomaterials
  • Cell Therapy Research
  • Pathology and Therapeutics


Roles and Responsibilities

Yasser is an expert in human immunology and cell biology. He has developed a research portfolio spanning molecular and cellular immunology, stem cells immunomodulation, biomarkers in translational and personalised medicine. Areas of particular interest include innate and adaptive immune responses in cancer, rheumatological disorders and regenerative medicine. Using primary derived cells, the phenotype and function of cells relating to specific diseases and states of inflammation are characterised. Specialist techniques of interest are flow cytometry, RT PCR and NanoString genetic profiling.

Other Team Members

Dr. Chris Gabbott
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Amy Kerry
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Prof John Hunt
Prof. John Hunt
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